Liquisolid: A Novel Technique for Dissolution Enhancement of Poorly Soluble Drugs
نویسندگان
چکیده
منابع مشابه
A New Crystal Engineering Technique for Dissolution Enhancement of Poorly Soluble Drugs Combining Quasi-emulsion and Crystallo-co Agglomeration Methods
A target of best dissolution improvement of poorly soluble drugs is a necessity for the success of formulation in industry. The present work describes the preparation, optimization, and evaluation of a new spherical agglomeration technique for glimepiride as a model of poorly soluble drugs. It involved the emulsification of a drug solution containing a dispersed carrier that tailors the crystal...
متن کاملA New Crystal Engineering Technique for Dissolution Enhancement of Poorly Soluble Drugs Combining Quasi-emulsion and Crystallo-co Agglomeration Methods
A target of best dissolution improvement of poorly soluble drugs is a necessity for the success of formulation in industry. The present work describes the preparation, optimization, and evaluation of a new spherical agglomeration technique for glimepiride as a model of poorly soluble drugs. It involved the emulsification of a drug solution containing a dispersed carrier that tailors the crystal...
متن کاملLiquisolid Compacts: An Effective Approach towards Enhancement of Dissolution Rate of Poorly Soluble Drugs
Department of pharmaceutics, Hindu College of Pharmacy, Guntur, Andhra Pradesh, India. ______________________________________________________________________ ABSTRACT Poorly water-soluble drugs involve many difficulties in the development of pharmaceutical dosage forms for oral delivery systems due to their low bioavailability. Therapeutic effectiveness of a drug depends upon the bioavailabilit...
متن کاملDissolution Enhancement of Poorly Soluble Drugs by Using Complexation Technique – A Review
Orally administered drugs completely absorb only when they show fair solubility in gastric medium and shows good bioavailability. The solubility properties of drug play an important role in the process of formulation developments. Problem of solubility can be solved by different approaches. Each approach suffers with some limitations and advantages. Among all, complexation techinque has been em...
متن کاملLiquisolid technique as a tool for enhancement of poorly water-soluble drugs and evaluation of their physicochemical properties.
The potential of liquisolid systems to improve the dissolution properties of a water-insoluble agent (indomethacin) was investigated. In this study, different formulations of liquisolid tablets using different co-solvents (non-volatile solvents) were prepared and the effect of aging on the dissolution behaviour of indomethacin liquisolid compacts was investigated. To evaluate any interaction be...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Current Pharma Research
سال: 2012
ISSN: 2230-7834,2230-7842
DOI: 10.33786/jcpr.2012.v03i01.008